https://chrpalmes.r-universe.devRecent package updates in chrpalmesR-universehttps://github.com/chrpalmes.pnghttps://chrpalmes.r-universe.devSat, 12 Sep 2026 14:10:39 GMTchristian.palmes@bayer.com (Christian Palmes)Computes optimal axis-aligned hyperrectangles for discrete binary arrays and continuous regions defined by quadratic response functions. The package provides methods for discrete optimization, grid classification, continuous refinement, and exact global extrema calculations. Applications include the identification of practical operating regions within multivariate design spaces, including pharmaceutical development settings related to ICH Q8.https://github.com/r-universe/chrpalmes/actions/runs/34822232821Sat, 12 Sep 2026 14:10:39 GMTOptOR0.1.0successhttps://chrpalmes.r-universe.devhttps://github.com/cran/OptORgetting-started.Rmdgetting-started.htmlGetting Started with OptOR2026-09-12 14:10:392026-09-12 14:10:39