Package: OptOR Type: Package Title: Optimal Hyperrectangular Operating Regions Version: 0.1.0 Authors@R: c( person( given = "Christian", family = "Palmes", role = c("aut", "cre"), email = "christian.palmes@bayer.com" ), person( given = "Bayer AG", role = "cph" ), person( given = "Raluca Ilinca", family = "Schmitt", role = "ctb", email = "raluca_ilinca.schmitt@bayer.com" ), person( given = "Adrian", family = "Funke", role = "ctb", email = "adrian.funke@bayer.com" ) ) Language: en-US Description: Computes optimal axis-aligned hyperrectangles for discrete binary arrays and continuous regions defined by quadratic response functions. The package provides methods for discrete optimization, grid classification, continuous refinement, and exact global extrema calculations. Applications include the identification of practical operating regions within multivariate design spaces, including pharmaceutical development settings related to ICH Q8. License: MIT + file LICENSE Encoding: UTF-8 NeedsCompilation: yes Imports: stats Suggests: ggplot2, grid, knitr, rmarkdown, testthat (>= 3.0.0) VignetteBuilder: knitr Config/testthat/edition: 3 Config/roxygen2/version: 8.0.0 Packaged: 2026-10-14 08:07:57 UTC; root Author: Christian Palmes [aut, cre], Bayer AG [cph], Raluca Ilinca Schmitt [ctb], Adrian Funke [ctb] Maintainer: Christian Palmes Repository: https://chrpalmes.r-universe.dev Date/Publication: 2026-09-12 14:10:39 UTC RemoteUrl: https://github.com/cran/OptOR RemoteRef: HEAD RemoteSha: a26e90bb2e21be5adfd31a280ca761ef8748cac0